Syngeneic Models

Cancer immunotherapies are designed to cooperating with a patient's own immune system to increase native anti-tumor responses. The conventional xenograft models lack relevance due to the animals’ immunocompromised status.  Syngeneic mouse models, however, are established by injecting tumor cells from the same genetic background as the given immuno-competent mouse strain, therefore, provides an effective approach in studying how cancer therapies response in the presence of a functional immune system and have become a reliable models for immunotherapy studies

MB Biosciences offers syngeneic cell line derived models for your research on tumor drug discovery as shown in the following table.

If you have any special requirements, please contact us; we are happy to work with you to develop a specific model at your request.