P450 Substrates and Metabolites
Cytochrome P450 substrates and their corresponding metabolites are commonly used in early-stage drug discovery services. These substrates can identify a compound’s ability to prevent the production of specific metabolites to help you expedite drug candidate selection.
MB Biosciences offers an extensive list of cytochrome P450 substrates and metabolites. They are supplied at high purity and in convenient package sizes to easily meet the unique needs of any study.
Contact for more information on cytochrome P450 substrate and metabolite products
| Product | Description | Volume |
|---|---|---|
| CYP500 | 4-hydroxydiclofenac | 0.1 mg |
| CYP500-5 | 4-hydroxydiclofenac | 5 mg |
| CYP501 | 6α-hydroxypaclitaxel | 0.1 mg |
| CYP501-5 | 6α-hydroxypaclitaxel | 5 mg |
| CYP505 | Tolbutamide | 100 mg |
| CYP506 | Hydroxytolbutamide | 10 mg |
| CYP507 | Carboxytolbutamide | 10 mg |
| CYP508 | Carboxytolbutamide methyl ester | 10 mg |
| CYP509 | Tolbutamide kit (CYP505 - CYP508) | - |
| CYP510 | 7-Ethoxyresorufin | 10 mg |
| CYP511 | Resorufin | 100 mg |
| CYP512 | 7-benzyloxyquinoline | 10 mg |
| CYP513 | 7-hydroxyquinoline | 10 mg |
| CYP515-10 | MAMC | 10 mg |
| CYP515-25 | MAMC | 25 mg |
| CYP516 | HAMC | 10 mg |
| CYP517-10 | 7-Methoxy-4-(trifluoromethyl)-coumarin (MFC) | 10 mg |
| CYP517-25 | 7-Methoxy-4-(trifluoromethyl)-coumarin (MFC) | 25 mg |
| CYP519 | 7-Hydroxy-4-(trifluoromethyl)-coumarin (HFC) | 10 mg |
| CYP520 | Omeprazole | 1 g |
| CYP521-10 | 3-O-methyfluorescein | 10 mg |
| CYP521-25 | 3-O-methyfluorescein | 25 mg |
| CYP522-10 | Tienilic acid | 10 mg |
| CYP522-25 | Tienilic acid | 25 mg |
| CYP523-25 | Paclitaxel | 25 mg |
| CYP523-100 | Paclitaxel | 100 mg |
| CYP524-100 | Ketoconazole | 100 mg |
| CYP524-1000 | Ketoconazole | 1 g |
| CYP525 | Diclofenac | 10 g |
| CYP526 | Amodiaquine dihydrochloride dihydrate | 5 g |
| CYP527-10 | Desethylamodiaquine | 10 mg |
| CYP527-25 | Desethylamodiaquine | 25 mg |
| CYP528 | Terfenadine | 5 g |
| CYP529-10 | R(-)-3-benzylphenobarbital | 10 mg |
| CYP529-25 | R(-)-3-benzylphenobarbital | 25 mg |
| CYP532 | S-mephenytoin | 5 mg |
| CYP533 | -4'-hydroxymephenytoin | 5 mg |